Investigation of cell biomechanics and the effect of biomechanical stimuli on cancer and their characteristics

Document Type : English

Authors

1 Biotechnology Department., Falavarjan Branch, Islamic Azad University, Isfahan, Iran

2 Institute of Psychiatry, Psychiatry and Neuroscience, Kings College London, London, UK

3 Department of Mechanical Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran

Abstract

Physical stimuli have a great impact on the survival, behavior, and function of all life. Recently, a theory has been proposed to understand cellular behavior in times of failure and disease, stating that cellular processes and damage can be affected by mechanical forces. Scientific evidence suggests that mechanical changes can affect many of the primary cellular mechanisms, as well as important aspects of cell behavior such as cell adhesion, movement, and signal transmission. In this study, we examine the history of the effects of mechanical stimulation from the beginning to the present, what is cell biomechanics, introduce features and methods to study cell characteristics such as micropipette suction and atomic force microscopy (AFM). In addition, to consider the effects of biomechanical stimulation it should be point out to cells using stimuli which can be useful including inducing differentiation into stem cells to produce bone cells that are applied by special devices that are briefly examined for the beneficial effects. It also has negative aspects for the cell, such as the occurrence of metastases in cancer cells. In this work, the effect of changes in the inclination, frequency and strain on the cancer cell was also investigated.

Keywords


 
[1] Majid, H., Atefeh, S., Nabiollah, A., Nooshin, H., Mahnaz, E., & Mohammad Ali, S. (2013). Effect of mechanical stimulations on the fate of stem cells-a review
[2] Suresh, S. (2007). Biomechanics and biophysics of cancer cells. Acta Materialia55(12), 3989-4014.
[3] Jacobs CR, Huang H, Kwon RY. Introduction to Cell Mechanics and Mechanobiology. Garland Science. 2013.
 [4] Evans EA, Skalak R. Mechanics and thermodynamics of biomembranes. Boca Raton, Florida. 1980..
[5] Wu X, Sun Z, Meininger GA, Muthuchamy M. Application of atomic force microscopy measurements on
 [6] Ross TD, Coon BG, Yun S, Baeyens N, Tanaka K, Ouyang M, Schwartz MA. Integrins in mechanotransduction. Curr Opin Cell Biol 2013; 25(5): 613-8.
[7] Goldstein LSB, Schneider M. Stem cells for dummies. Hoboken, NJ: Wiley Publishing, Inc, 2010; p: 19-25, 99-119.
[8] Sim WY, Park SW, Park SH, Min BH, Park SR, Yang SS. A pneumatic micro cell chip for the differentiation of human mesenchymal stem cells under mechanical stimulation. Lab Chip 2007; 7(12): 1775-82.
[9] Kasper C, Griensven M, Portner R, Al-Rubeai M. Bioreator systems for tissue engineering. Berlin: Springer, 2009; p: 95-125.
[10] Kim JH,Cho CS, Choung YH, Lim KT, Son HM, Seonwoo H, Baik SJ, Jeon SH, Park JY, Choung PH, Chung JH. Mechanical stimulation of mesenchymal stem cells for tissue engineering. TERM 2009; 6(1): 199-206
[11] Navidbakhsh, M., & Jaafarnejad, M. (2010). Modeling the Effects of Biomechanical Factors on the Deformability of Metastatic Cancer Cells. Iranian Journal of Biomedical Engineering3, 399-306
[12] Shamsehkohan, P., & Sadeghi, H. (2017). Overview of the mechanical function of tissue cells affecting human movement. Scientific Journal of Rehabilitation Medicine5(4), 271-281.
[13] Saeedi, M. R., Morovvati, M. R., & Mollaei-Dariani, B. (2020). Experimental and numerical investigation of impact resistance of aluminum–copper cladded sheets using an energy-based damage model. Journal of the Brazilian Society of Mechanical Sciences and Engineering, 42(6), 1-24.
[14] Kardan-Halvaei, M., Morovvati, M. R., & Mollaei-Dariani, B. (2020). Crystal plasticity finite element simulation and experimental investigation of the micro-upsetting process of OFHC copper. Journal of Micromechanics and Microengineering, 30(7), 075005.
[15] Fazlollahi, M., Morovvati, M. R., & Mollaei Dariani, B. (2019). Theoretical, numerical and experimental investigation of hydro-mechanical deep drawing of steel/polymer/steel sandwich sheets. Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, 233(5), 1529-1546.
[16] Saeedi, M. R., Morovvati, M. R., & Alizadeh-Vaghasloo, Y. (2018). Experimental and numerical study of mode-I and mixed-mode fracture of ductile U-notched functionally graded materials. International Journal of Mechanical Sciences, 144, 324-340.
[17] Morovvati, M. R., & Mollaei-Dariani, B. (2018). The formability investigation of CNT-reinforced aluminum nano-composite sheets manufactured by accumulative roll bonding. The International Journal of Advanced Manufacturing Technology, 95(9), 3523-3533.
[18] Morovvati, M. R., & Dariani, B. M. (2017). The effect of annealing on the formability of aluminum 1200 after accumulative roll bonding. Journal of Manufacturing Processes, 30, 241-254.
[19] Morovvati, M. R., Lalehpour, A., & Esmaeilzare, A. (2016). Effect of nano/micro B4C and SiC particles on fracture properties of aluminum 7075 particulate composites under chevron-notch plane strain fracture toughness test. Materials Research Express, 3(12), 125026.
[20] Fatemi, A., Morovvati, M. R., & Biglari, F. R. (2013). The effect of tube material, microstructure, and heat treatment on process responses of tube hydroforming without axial force. The International Journal of Advanced Manufacturing Technology, 68(1), 263-276.
[21] Pourmoghadam, M. N., Esfahani, R. S., Morovvati, M. R., & Rizi, B. N. (2013). Bifurcation analysis of plastic wrinkling formation for anisotropic laminated sheets (AA2024–Polyamide–AA2024). Computational materials science, 77, 35-43.
[22] Morovvati, M. R., Fatemi, A., & Sadighi, M. (2011). Experimental and finite element investigation on wrinkling of circular single layer and two-layer sheet metals in deep drawing process. The International Journal of Advanced Manufacturing Technology, 54(1), 113-121.
[23] Morovvati, M. R., Mollaei-Dariani, B., & Haddadzadeh, M. (2010). Initial blank optimization in multilayer deep drawing process using GONNS. Journal of manufacturing science and engineering, 132(6).
[24] Fatemi, A., Biglari, F., & Morovvati, M. R. (2010). Influences of inner pressure and tube thickness on process responses of hydroforming copper tubes without axial force. Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, 224(12), 1866-1878.
[25] Khandan, A., Abdellahi, M., Ozada, N., & Ghayour, H. (2016). Study of the bioactivity, wettability and hardness behaviour of the bovine hydroxyapatite-diopside bio-nanocomposite coating. Journal of the Taiwan Institute of Chemical Engineers, 60, 538-546.
[26] Karamian, E., Motamedi, M. R. K., Khandan, A., Soltani, P., & Maghsoudi, S. (2014). An in vitro evaluation of novel NHA/zircon plasma coating on 316L stainless steel dental implant. Progress in Natural Science: Materials International, 24(2), 150-156.
[27] Karamian, E., Abdellahi, M., Khandan, A., & Abdellah, S. (2016). Introducing the fluorine doped natural hydroxyapatite-titania nanobiocomposite ceramic. Journal of Alloys and Compounds, 679, 375-383.
[28] Ghayour, H., Abdellahi, M., Ozada, N., Jabbrzare, S., & Khandan, A. (2017). Hyperthermia application of zinc doped nickel ferrite nanoparticles. Journal of Physics and Chemistry of Solids, 111, 464-472.
[29] Kazemi, A., Abdellahi, M., Khajeh-Sharafabadi, A., Khandan, A., & Ozada, N. (2017). Study of in vitro bioactivity and mechanical properties of diopside nano-bioceramic synthesized by a facile method using eggshell as raw material. Materials Science and Engineering: C, 71, 604-610.
[30] Khandan, A., & Ozada, N. (2017). Bredigite-Magnetite (Ca7MgSi4O16-Fe3O4) nanoparticles: A study on their magnetic properties. Journal of Alloys and Compounds, 726, 729-736.
[31] Khandan, A., Jazayeri, H., Fahmy, M. D., & Razavi, M. (2017). Hydrogels: Types, structure, properties, and applications. Biomat Tiss Eng, 4(27), 143-69.
[32] Khandan, A., & Ozada, N. (2017). A novel and economical route for synthesizing akermanite (Ca2MgSi2O7) nano-bioceramic. Materials Science and Engineering: C, 71, 1072-1078.
[33] Heydary, H. A., Karamian, E., Poorazizi, E., Khandan, A., & Heydaripour, J. (2015). A novel nano-fiber of Iranian gum tragacanth-polyvinyl alcohol/nanoclay composite for wound healing applications. Procedia Materials Science, 11, 176-182.
[34] Khandan, A., Karamian, E., & Bonakdarchian, M. (2014). Mechanochemical synthesis evaluation of nanocrystalline bone-derived bioceramic powder using for bone tissue engineering. Dental Hypotheses, 5(4), 155.
[35] Karamian, E., Khandan, A., Kalantar Motamedi, M. R., & Mirmohammadi, H. (2014). Surface characteristics and bioactivity of a novel natural HA/zircon nanocomposite coated on dental implants. BioMed research international, 2014.
[36] Jabbarzare, S., Abdellahi, M., Ghayour, H., Arpanahi, A., & Khandan, A. (2017). A study on the synthesis and magnetic properties of the cerium ferrite ceramic. Journal of Alloys and Compounds, 694, 800-807.
[37] Razavi, M., & Khandan, A. (2017). Safety, regulatory issues, long-term biotoxicity, and the processing environment. In Nanobiomaterials Science, Development and Evaluation (pp. 261-279). Woodhead Publishing.
[38] Karamian, E. B., Motamedi, M. R., Mirmohammadi, K., Soltani, P. A., & Khandan, A. M. (2014). Correlation between crystallographic parameters and biodegradation rate of natural hydroxyapatite in physiological solutions. Indian J Sci Res, 4(3), 092-9.
[39] Rashid, B., Destrade, M., and Gilchrist, M.D., "Inhomogeneous Deformation of Brain Tissue during Tension Tests", Computational Materials Science, Vol. 64, pp. 295-300, (2012).
[40] Feng, Y., Okamoto, R.J., Namani, R., Genin, G.M., and Bayly, P.V., "Measurements of Mechanical Anisotropy in Brain Tissue and Implications for Transversely Isotropic Material Models of White Matter", Journal of the Mechanical Behavior of Biomedical Materials, Vol. 23, pp. 117-132, (2013).
[41] Laksari, K., Shafieian, M., and Darvish, K., "Constitutive Model for Brain Tissue under Finite Compression", Journal of Biomechanics, Vol. 45, No. 4, pp. 642-646, (2012).
[42] Heydari, E., Mokhtarian, A., Pirmoradian, M., Hashemian, M., & Seifzadeh, A. (2020). Sound transmission loss of a porous heterogeneous cylindrical nanoshell employing nonlocal strain gradient and first-order shear deformation assumptions. Mechanics Based Design of Structures and Machines, 1-22.
[43] Torkan, E., & Pirmoradian, M. (2019). Efficient higher-order shear deformation theories for instability analysis of plates carrying a mass moving on an elliptical path. Journal of Solid Mechanics, 11(4), 790-808.
[44] Torkan, E., Pirmoradian, M., & Hashemian, M. (2019). Dynamic instability analysis of moderately thick rectangular plates influenced by an orbiting mass based on the first-order shear deformation theory. Modares Mechanical Engineering, 19(9), 2203-2213.
[45] Torkan, E., Pirmoradian, M., & Hashemian, M. (2017). Occurrence of parametric resonance in vibrations of rectangular plates resting on elastic foundation under passage of continuous series of moving masses. Modares Mechanical Engineering, 17(9), 225-236.
[46] Pirmoradian, M., Torkan, E., Zali, H., Hashemian, M., & Toghraie, D. (2020). Statistical and parametric instability analysis for delivery of nanoparticles through embedded DWCNT. Physica A: Statistical Mechanics and Its Applications, 554, 123911.
[47] Pirmoradian, M., Torkan, E., & Toghraie, D. (2020). Study on size-dependent vibration and stability of DWCNTs subjected to moving nanoparticles and embedded on two-parameter foundations. Mechanics of Materials, 142, 103279.
[48] Pirmoradian, M., & Karimpour, H. (2017). Parametric resonance and jump analysis of a beam subjected to periodic mass transition. Nonlinear Dynamics, 89(3), 2141-2154.
[49] Heydari, S., Attaeyan, A., Bitaraf, P., Gholami, A., Kamyab Moghadas, B. (2021). Investigation of modern ceramics in bioelectrical engineering with proper thermal and mechanical properties. Journal of Simulation and Analysis of Novel Technologies in Mechanical Engineering, 13(3), 43-52.
[50] Heydari, S., Sadat Mirinejad, M., Malekipour Esfahani, M., Karimian, F., Attaeyan, A., Latifi, M. (2021). A brief review on titanium alloy for dental, biotechnology and biomedical applications. Journal of Simulation and Analysis of Novel Technologies in Mechanical Engineering, 13(2), 47-58.