Document Type : English
Dental Students Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
Faculty of Dentistry, Qom University of Medical Sciences, Qom, Iran
Private practice, Dental School, Shiraz University of Medical Sciences, Shiraz, Iran
Department of Mechanical Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran
Bioactive glass has been used successfully as a bone filler in dental surgery. Recently, attention has focused on researching the production of bioactive glass (BG) through sol-gel reactions. Among natural ceramics, BG has proper mechanical and chemical stability compared to conventional ceramics. These materials have certain biological and chemical properties such as proper biocompatibility and biodegradability. one of the strengths is its biocompatibility and biodegradability and lack of immune response besides its proper mechanical properties of about 500 MPa which has about the maximum of 180 MPa mechanical strength. The BG bio-ceramic is primarily used to repair bone and tooth damage or defects that can be reproduced by natural processes. The first successful surgery used in 45S5 bioglass was to replace the middle ear bones to solve the auditory conduction problem. Also, the microscopic analysis of pulp cells with 45S5 bio-glass produced shows the least toxic effect. Bioglass 45S5 can act as a biocompatible material that could potentially be used safely on dentin.